Scientific References

Amaechi, B. T., Lemke, K. C., Saha, S., Luong, M. N., & Gelfond, J. (2021). Clinical efficacy of nanohydroxyapatite-containing toothpaste at relieving dentin hypersensitivity: An 8 weeks randomized control trial. BDJ Open, 7(23), 1–8. https://doi.org/10.1038/s41405-021-00080-7

Bauer, J. A., Zámocká, M., Majtán, J., & Bauerová-Hlinková, V. (2022). Glucose oxidase, an enzyme "ferrari": Its structure, function, production and properties in the light of various industrial and biotechnological applications. Biomolecules, 12(3), 472. https://doi.org/10.3390/biom12030472

Berlutti, F., Pilloni, A., Pietropaoli, M., Polimeni, A., & Valenti, P. (2012). Lactoferrin and oral diseases: Current status and perspective in periodontitis. Annali Di Stomatologia, 2(3-4), 10–18.

Chen, S. Y., Delacruz, J., Kim, Y., Kingston, R., Purvis, L., & Sharma, D. (2023). Effect of xylitol on Porphyromonas gingivalis: A systematic review. Clinical and Experimental Dental Research, 9(2), 265–275. https://doi.org/10.1002/cre2.724

Ciccotosto, G. D., Mohammed, A. I., Paolini, R., Bijlsma, E., Toulson, S., Holden, J., Reynolds, E. C., Dashper, S. G., & Butler, C. A. (2024). Chronic oral inoculation of Porphyromonas gingivalis and Treponema denticola induce different brain pathologies in a mouse model of alzheimer disease. The Journal of Infectious Diseases, 230(2), S109–S116. https://doi.org/10.1093/infdis/jiae286

Farooq, I., & Bugshan, A. (2021). The role of salivary contents and modern technologies in the remineralization of dental enamel: A narrative review. F1000Research, 9(3), 171. https://doi.org/10.12688/f1000research.22499.3

Lei, S., Li, J., Yu, J., Li, F., Pan, Y., Chen, X., Ma, C., Zhao, W., & Tang, X. (2023). Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway. International Journal of Oral Science, 15(1), 1–12. https://doi.org/10.1038/s41368-022-00215-y

Liu, N., Li, X., Wang, M., Zhang, F., Wang, C., Zhang, K., Wang, H., Xu, S., Hu, W., & Gu, L. (2021). DexA70, the truncated form of a self-produced dextranase, effectively disrupts Streptococcus mutans biofilm. Frontiers in Microbiology, 12, 737458. https://doi.org/10.3389/fmicb.2021.737458

Magacz, M., Kędziora, K., Sapa, J., & Krzyściak, W. (2019). The significance of lactoperoxidase system in oral health: Application and efficacy in oral hygiene products. International Journal of Molecular Sciences, 20(6), 1443. https://doi.org/10.3390/ijms20061443

Najibfard, K., Ramalingam, K., Chedjieu, I., & Amaechi, B. T. (2011). Remineralization of early caries by a nano-hydroxyapatite dentifrice. The Journal of Clinical Dentistry, 22(5), 139–143.

Pepla, E., Besharat, L. K., Palaia, G., Tenore, G., & Migliau, G. (2014). Nano-hydroxyapatite and its applications in preventive, restorative and regenerative dentistry: A review of literature. Annali Di Stomatologia, 5(3), 108–114.

Rikvold, P. D., Benedicte, L., Meyer, R. L., Jørgensen, M. R., Tiwari, M. K., & Schlafer, S. (2023). The effect of enzymatic treatment with mutanase, Beta-Glucanase, and DNase on a saliva-derived Biofilm model. Caries Research, 58(2), 72–80. https://doi.org/10.1159/000535980

Ryder, M. I. (2020). Porphyromonas gingivalis and alzheimer disease: Recent findings and potential therapies. Journal of Periodontology, 91(1), 545–549. https://doi.org/10.1002/jper.20-0104